"Rugrats Go Wild" is an animated adventure that brings together two beloved Nickelodeon franchises: "Rugrats" and "The Wild Thornberrys." The story unfolds as the Rugrats, led by Tommy Pickles, embark on a family vacation aboard a cruise ship. However, their excitement takes a wild turn when they find themselves stranded on a deserted island after a storm capsizes their ship.

As the Rugrats explore their new surroundings, they encounter the Thornberry family, who are on a mission to document wildlife. The two groups of kids quickly bond, with Eliza Thornberry using her unique ability to communicate with animals to help them navigate the challenges of island life. Together, they face various adventures, from befriending exotic creatures to overcoming obstacles that test their teamwork and courage.

Amidst the fun and chaos, the film emphasizes themes of friendship, bravery, and the importance of family. With humor and heartwarming moments, "Rugrats Go Wild" captures the essence of childhood exploration and the joy of discovering the world around us.