Hardened Arizona rancher Jim Hanson simply wants to be left alone as he fends off eviction notices and tries to make a living on an isolated stretch of borderland. But everything changes when Hanson, an ex-Marine, witnesses 11-year-old migrant Miguel fleeing with his mother Rosa from drug cartel assassins led by the ruthless Mauricio. After being caught in a shoot-out, an injured Rosa begs Jim to take her son to safety to her family in Chicago. Defying his step-daughter Sarah, Jim sneaks Miguel out of the local U.S. Customs and Border Patrol station and together, they hit the road with the group of killers in pursuit. Jim and Miguel slowly begin to overcome their differences and begin to forge an unlikely friendship, while Mauricio and his fellow assassins blaze a cold-blooded trail, hot on their heels.