The story begins when ace detective Harry Goodman goes mysteriously missing, prompting his 21 year old son Tim to find out what happened. Aiding in the investigation is Harry’s former Pokemon partner, Detective Pikachu: a hilariously wise-cracking, adorable super-sleuth who is a puzzlement even to himself. Finding that they are uniquely equipped to work together, as Tim is the only human who can talk with Detective Pikachu, they join forces on a thrilling adventure to unravel the tangled mystery. Chasing clues together through the neon-lit streets of Ryme City—a sprawling, modern metropolis where humans and Pokemon live side by side in a hyper-realistic live-action world—they encounter a diverse cast of Pokemon and uncover a shocking plot that could destroy this peaceful co-existence and threaten the whole Pokemon universe.