Against the wishes of her overprotective father, Tiffany insists on spending her 18th birthday at an all-night Halloween frat party at remote lake that was once the scene of a gruesome murder. At the lake, she’s too busy flirting with frat president Jonathan to notice that her fellow partiers are being picked off one by one by a pair of chainsaw-wielding madmen. Concerned for her safety, Tiffany’s irrepressible great-aunt Madea drags her elderly companions Uncle Joe, Aunt Bam and Hattie out to the woods to rescue her. But when the terrified seniors encounter a series of ghostly apparitions and masked killers, they’re the ones in need of rescuing.